Dr Achim Weber, an expert from Fraunhofer IGB, explained the advantages of additive manufacturing based on the results of the European TriAnkle project at the Formnext trade show in Frankfurt last November.
‘The TriAnkle project has developed a manufacturing process for customised implants that can be used in the treatment of tendon and joint injuries of the foot. Customised cartilage and tendon implants made from specially modified biomaterials allow us to mimic the natural tissue environment and promote fast and efficient regeneration. Multi-material technology allows us to customise mechanical properties and embed specific cells and growth factors,’ said Achim Weber.
Bioinks for cartilage and tendon replacement: progress of the TriAnkle project
Tendon and cartilage damage caused by ageing processes or sporting activities is a frequent cause of long-term ailments and impaired quality of life worldwide. ‘Therefore, as part of the TriAnkle project, we have developed innovative 3D bioprinting technologies that are particularly suitable for orthopaedic applications. Until now, many therapeutic approaches have only been able to partially restore the original mechanical and biological function of the damaged tissue. This is where TriAnkle comes in. With customised cartilage and tendon implants made from modified biomaterials, we aim to recreate the natural extracellular environment of orthopaedic soft tissue as accurately as possible. Using methacrylated biomaterials and photopolymerised hydrogels, we have been able to develop 3D printed, patient-specific implants with layered structures and a high degree of flexibility,’ Achim Weber explained.
Advantages of multi-material technology
At Formnext, Achim Weber explained the advantages of the multi-material technology applied in TriAnkle. ‘The stiffness of the hydrogels can be customised to simulate the mechanical properties of cartilage and tendon tissue. The porous structure of the matrix allows optimal embedding of cells and growth factors. The multi-material technology supports fast and efficient regeneration of damaged soft tissue and thus promises a less invasive and long-lasting form of therapy’.
